Frontotemporal Lobar Degeneration with FUS inclusions (FTLD-FUS) is a subtype of Frontotemporal Lobar Degeneration (FTLD), a group of neurodegenerative disorders. FTLD is characterized by the progressive loss of neurons in the frontal and temporal lobes of the brain. In FTLD-FUS, the pathological hallmark is the accumulation of misfolded protein inclusions containing fused in sarcoma (FUS) protein.
