Ferric reductase is an enzyme that plays a critical role in the reduction of ferric (Fe3+) ions to ferrous (Fe2+) ions. This process is essential for the proper absorption of iron in the intestine and its mobilization within various tissues. Ferric reductase is an integral membrane protein located primarily in the brush border of enterocytes in the small intestine. Its activity is crucial for maintaining iron homeostasis in the body.