Endomitosis is a specialized form of cell division that occurs during megakaryopoiesis. Unlike typical mitosis, endomitosis involves the replication of the cell's DNA without cytokinesis, resulting in a cell with multiple copies of its DNA. This leads to the formation of polyploid megakaryocytes, which can have up to 64 copies of the DNA. This polyploidy is essential for the large-scale production of platelets.
