Several histological techniques are commonly used in drug development, including:
Hematoxylin and Eosin (H&E) Staining: A standard technique for evaluating tissue morphology. Immunohistochemistry (IHC): Used to detect specific proteins within tissue sections, aiding in the identification of cellular targets and pathways affected by the drug. In Situ Hybridization (ISH): Allows for the localization of specific nucleic acid sequences within tissues. Special Stains: Techniques such as Masson's Trichrome for collagen detection or Periodic Acid-Schiff (PAS) for polysaccharides.
