What Histological Features Indicate Poor Prognosis?
Several histological features can signal a poor prognosis and reduced survival rates. These include:
Cellular atypia: Abnormal cell structures often correlate with malignancy and aggressive disease. High mitotic index: A high number of cells undergoing division suggests rapid tumor growth. Necrosis: Dead cell areas within tumors usually indicate aggressive behavior and poor response to treatment. Lymphovascular invasion: Cancer cells found in lymphatic or blood vessels can lead to metastasis, reducing survival chances.
