What histological changes occur in the nervous system with aging?
In the nervous system, aging is characterized by a loss of neurons, particularly in areas such as the hippocampus and cerebral cortex. There is also an accumulation of protein aggregates, such as amyloid plaques and neurofibrillary tangles, which are implicated in neurodegenerative diseases like Alzheimer's. Additionally, myelin sheaths deteriorate, impairing nerve signal transmission.
