During an infection, several histological changes can occur, including: - Inflammation: This is a common response to infection, characterized by the influx of immune cells such as neutrophils and macrophages. Histologically, you may observe an increase in these cells in the affected tissue. - Tissue Necrosis: Some pathogens produce toxins that cause cell death. This can be seen as areas of necrosis in tissue samples. - Granuloma Formation: In diseases like tuberculosis, the body forms granulomas to contain the pathogen. These are aggregates of macrophages, often with a central area of necrosis.
