What Histological Changes Are Observed in Vasopressin-Secreting Cells?
Histologically, the neurons in the supraoptic and paraventricular nuclei that produce vasopressin exhibit large cell bodies and prominent nuclei. These neurons often contain dense-core vesicles, which store vasopressin. In the posterior pituitary gland, the axon terminals of these neurons are seen as Herring bodies, which are accumulations of secretory granules containing vasopressin and its carrier protein, neurophysin.