Several histological changes can be observed in UTIs, including: - Inflammatory Infiltrates: The presence of immune cells, such as neutrophils and macrophages, is a hallmark of infection. - Epithelial Changes: The urothelium (lining of the urinary tract) may show signs of damage, such as ulceration and sloughing. - Vascular Changes: Increased vascularization and congestion are often observed, contributing to the redness and swelling associated with infection.