What Conditions Can Cause Elevated Urinary Porphyrins?
Several conditions can lead to elevated urinary porphyrins, including acute intermittent porphyria (AIP), variegate porphyria (VP), and hereditary coproporphyria (HCP). These conditions are often characterized by a combination of neurovisceral symptoms, such as abdominal pain, neuropathy, and psychiatric symptoms, along with cutaneous manifestations in some cases. Elevated urinary porphyrins can also be seen in some cases of lead poisoning and liver disease.