Several clinical conditions can affect spongy bone, including: - [Osteoporosis](https://): A condition characterized by decreased bone mass and density, leading to fragile bones and increased risk of fractures. - [Osteomalacia](https://): Softening of bones due to defective bone mineralization, often caused by vitamin D deficiency. - [Bone marrow disorders](https://): Conditions like leukemia and myelofibrosis that affect the bone marrow's ability to produce blood cells.
Understanding the histological features and functions of spongy bone is crucial for diagnosing and treating various bone-related disorders, as well as for developing strategies to enhance bone health and regeneration.