What Challenges are Associated with Tissue Homogenates?
While tissue homogenates are invaluable, several challenges can arise during their preparation and analysis:
Sample Integrity: Improper handling can lead to degradation of proteins, DNA, or RNA. Cross-Contamination: Ensuring that samples are not contaminated with foreign material is crucial. Homogenization Efficiency: Achieving a uniform homogenate can be difficult, especially with tough or fibrous tissues.