What Challenges are Associated with Cell Delivery?
Despite its potential, cell delivery faces several challenges:
Cell Viability: Ensuring that cells remain alive and functional during and after delivery is critical. Factors such as shear stress, immune response, and nutrient availability can impact viability. Immune Rejection: The host immune system may recognize delivered cells as foreign and mount an immune response, leading to rejection. Integration: Delivered cells must integrate with the host tissue, which involves forming connections with the existing cells and extracellular matrix. Controlled Release: Achieving a controlled and sustained release of cells to the target site can be challenging, especially in dynamic biological environments.
