Pathological cell death can be triggered by a variety of factors, including:
Physical Injury: Trauma or mechanical damage can cause cells to undergo necrosis. Infection: Bacterial, viral, or fungal infections can induce cell death through direct cytopathic effects or through the host’s immune response. Toxins: Exposure to toxic substances can disrupt cellular homeostasis, leading to cell death. Ischemia: Lack of blood flow, and hence oxygen, can result in cell death through necrosis or ischemia-reperfusion injury.