Pathological cell death can have several impacts on tissues, including:
Inflammation: Necrosis often triggers an inflammatory response, which can lead to further tissue damage and complicate healing. Fibrosis: Chronic cell death can lead to the replacement of normal tissue with fibrous connective tissue, impairing organ function. Loss of Function: The death of functional cells can lead to a reduction in the organ's ability to perform its normal tasks. For example, the death of myocardial cells in the heart can lead to impaired cardiac function.