Several factors can lead to interstitial edema, including:
Increased capillary hydrostatic pressure: Often due to heart failure or venous obstruction, which forces more fluid out of the capillaries. Decreased plasma oncotic pressure: Usually resulting from hypoalbuminemia, where reduced levels of albumin in the blood decrease the osmotic gradient that normally pulls fluid back into the capillaries. Increased capillary permeability: Commonly associated with inflammation or allergic reactions, where the capillary walls become more permeable to fluid and proteins. Lymphatic obstruction: Can be caused by infections, tumors, or surgical removal of lymph nodes, leading to impaired drainage of interstitial fluid.