dilation of the endoplasmic reticulum

What Causes ER Dilation?

Several factors can cause ER dilation, including:
Protein misfolding and accumulation
Disturbances in calcium homeostasis
Exposure to toxins or drugs
Viral infections
Hypoxia (lack of oxygen)
These stressors can disrupt the normal function of the ER, leading to the activation of the unfolded protein response (UPR) and subsequent dilation.

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