What Can We Learn from Histological Analysis of Knockout Models?
Histological analysis of knockout models can reveal a plethora of information, including: - Changes in Cell Morphology: Alterations in cell shape, size, and structure. - Tissue Architecture: Disruptions or changes in the organization of tissues. - Cell Proliferation and Apoptosis: Differences in rates of cell division and programmed cell death. - Protein Localization: Changes in the distribution of proteins within cells and tissues. - Pathological Changes: Development of diseases or abnormal conditions that arise due to the absence of the gene.
