What Can We Learn from Histological Analysis of Knockout Models?

Histological analysis of knockout models can reveal a plethora of information, including:
- Changes in Cell Morphology: Alterations in cell shape, size, and structure.
- Tissue Architecture: Disruptions or changes in the organization of tissues.
- Cell Proliferation and Apoptosis: Differences in rates of cell division and programmed cell death.
- Protein Localization: Changes in the distribution of proteins within cells and tissues.
- Pathological Changes: Development of diseases or abnormal conditions that arise due to the absence of the gene.