A comprehensive system audit in a histology lab would typically cover: - Sample Handling: From collection to disposal, ensuring proper labeling and tracking. - Processing Protocols: Evaluating the procedures for tissue fixation, embedding, sectioning, and staining. - Instrumentation: Checking the calibration and maintenance records of all lab equipment. - Documentation: Reviewing records for accuracy, completeness, and compliance with standards. - Personnel Training: Ensuring staff are adequately trained and competent in their roles. - Safety Protocols: Assessing adherence to safety guidelines to protect staff and maintain a safe working environment.