What are the Treatment Options for Hypereosinophilic Syndrome?
Treatment aims to reduce eosinophil counts and manage organ-specific complications:
Corticosteroids: Often the first-line treatment to reduce eosinophil levels and inflammation. Immunosuppressive Agents: Such as hydroxyurea and methotrexate, used in steroid-resistant cases. Tyrosine Kinase Inhibitors: In cases driven by specific genetic mutations, drugs like imatinib can be effective. Biological Therapies: Monoclonal antibodies targeting interleukins involved in eosinophil activation, such as mepolizumab.