The treatment of GSDs depends on the specific type and severity of the disease:
- Dietary Management: Many GSDs, especially those affecting the liver (e.g., Type I), are managed with a specialized diet to maintain blood glucose levels. This may involve frequent meals, cornstarch supplements, and avoidance of fasting. - Enzyme Replacement Therapy: For Type II (Pompe Disease), enzyme replacement therapy with recombinant human acid alpha-glucosidase can be life-saving. - Gene Therapy: Emerging therapies aim to correct the underlying genetic defects in certain GSDs. - Supportive Care: Physical therapy, occupational therapy, and other supportive measures are important for managing muscle weakness and other complications.
