Tissue repair generally occurs in three overlapping stages: 1. Inflammation: This initial phase involves the recruitment of immune cells to remove debris and pathogens. 2. Proliferation: In this phase, fibroblasts proliferate and synthesize new ECM, while endothelial cells form new blood vessels through angiogenesis. 3. Remodeling: The final phase involves the maturation and reorganization of the ECM, culminating in the formation of a scar.
