Several cell types are pivotal in tissue repair, including fibroblasts, endothelial cells, and various immune cells. Fibroblasts play a central role by synthesizing the extracellular matrix (ECM) and collagen that form the structural framework of tissues. Endothelial cells are involved in forming new blood vessels during a process known as angiogenesis. Immune cells, such as macrophages, help eliminate debris and pathogens, and also release cytokines that modulate the repair process.
