1. MyoD: One of the first identified MRFs, MyoD is essential for the initiation of muscle differentiation. It activates muscle-specific genes and commits cells to the myogenic lineage. 2. Myf5: Myf5 is involved in the early stages of myogenesis, particularly in the specification of muscle progenitor cells. 3. Myogenin: This factor is crucial for the terminal differentiation of muscle cells. Myogenin works downstream of MyoD and Myf5 to promote the fusion of myoblasts into mature myotubes. 4. MRF4: MRF4, also known as Myf6, has roles in both early and late stages of muscle development, often in conjunction with other MRFs.
