What Are the Pathological Changes in Fiber Morphology?
Alterations in fiber morphology can indicate pathological conditions:
1. Fibrosis: An excessive deposition of collagen fibers can lead to tissue fibrosis, a hallmark of chronic inflammatory diseases such as liver cirrhosis and pulmonary fibrosis.
2. Elastic Fiber Degradation: Conditions like Marfan syndrome are characterized by defects in elastic fibers, leading to weakened connective tissue and symptoms such as aortic aneurysms.
3. Reticular Fiber Changes: Changes in the density and organization of reticular fibers can be observed in various hematological disorders and certain cancers.
