What are the Molecular Mechanisms Behind Invasiveness?
Several molecular mechanisms drive invasiveness. These include alterations in cell adhesion molecules, like reduced expression of E-cadherin, which normally helps cells stick together. Changes in signaling pathways, such as the activation of the epithelial-to-mesenchymal transition (EMT), also play a role. EMT transforms epithelial cells into a mesenchymal phenotype, enhancing their migratory and invasive capabilities.
