What Are the Microscopic Characteristics of Common Skin Conditions?
Different skin conditions exhibit unique histological features:
- Psoriasis: Characterized by hyperproliferation of keratinocytes, resulting in thickened epidermis (acanthosis) and elongated rete ridges. There is also parakeratosis (retention of nuclei in the stratum corneum) and Munro microabscesses (collections of neutrophils).
- Eczema: Displays spongiosis (intercellular edema in the epidermis), accompanied by inflammatory infiltrates predominantly composed of lymphocytes and eosinophils.
- Lichen Planus: Shows a band-like lymphocytic infiltrate at the dermoepidermal junction, with basal cell degeneration and a "saw-tooth" appearance of the rete ridges.
