The major components of the ECM include collagen, elastin, and glycoproteins such as fibronectin and laminin. Proteoglycans and glycosaminoglycans (GAGs) are also integral to the ECM.
- Collagen: The most abundant protein in the ECM, providing tensile strength. - Elastin: Provides elasticity, allowing tissues to resume their shape after stretching or contracting. - Fibronectin and Laminin: Glycoproteins involved in cell adhesion, growth, and differentiation. - Proteoglycans and GAGs: These molecules fill the interstitial space and provide hydration and resilience.
