What are the Key Pathological Features Observed in Histology?
Pathological features can vary widely depending on the tissue type and the disease in question. Some common features include:
Cellular Atypia: Abnormal appearance of cells, which can indicate malignancy. This includes changes in size, shape, and nuclear abnormalities. Inflammation: Presence of inflammatory cells like lymphocytes, macrophages, and neutrophils, which indicate an immune response to infection or injury. Necrosis: Cell death characterized by the loss of cell membrane integrity and uncontrolled release of cellular contents. Fibrosis: Excessive deposition of connective tissue, commonly seen in chronic inflammatory conditions. Edema: Accumulation of fluid within tissues, evident as spaces between cells. Hyperplasia and Hypertrophy: Increase in the number of cells and an increase in cell size, respectively, usually as a response to chronic irritation or hormonal signals.
