What Are the Key Histological Features of Malignant Tumors?
Several key features help in identifying malignant tumors histologically:
Pleomorphism: This refers to the variation in size and shape of cells and nuclei within the tumor. Hyperchromatism: The nuclei of tumor cells often appear darker due to an increased amount of DNA. Loss of Differentiation: Malignant cells often lose the specialized functions of the tissue they originate from. Invasion: Malignant tumors invade surrounding tissues, breaking through the basement membrane. Necrosis: Areas of cell death can be seen within malignant tumors due to rapid growth outpacing the blood supply.
