1. Reagent Quality: Ensuring the purity and efficacy of stains, fixatives, and other chemicals used in tissue processing. 2. Equipment Calibration: Regular calibration and maintenance of microtomes, cryostats, and microscopes to ensure precision and accuracy. 3. Standard Operating Procedures (SOPs): Implementing and adhering to SOPs for tissue processing, embedding, sectioning, and staining to maintain consistency. 4. Proficiency Testing: Regular participation in proficiency testing programs to assess the laboratory's performance against external standards. 5. Documentation: Keeping detailed records of QC measures, including reagent lot numbers, equipment maintenance logs, and test results.