What are the Implications of G Protein Transducin Dysfunction?
Mutations or dysfunction in the components of the phototransduction pathway, including transducin, can lead to various visual disorders. One such condition is congenital stationary night blindness (CSNB), where affected individuals have difficulty seeing in low light due to impaired rod function. Another related disorder is retinitis pigmentosa (RP), a group of genetic disorders that cause progressive vision loss due to the degeneration of photoreceptor cells. Understanding the role of transducin in these conditions helps in developing potential therapeutic strategies.
