What are the Implications of Basement Membrane Thickening?
Thickening of the basement membrane can have significant implications for tissue function. It can lead to impaired diffusion of nutrients and waste products, altered cell signaling, and compromised tissue repair mechanisms. In organs like the kidneys, basement membrane thickening can contribute to glomerulosclerosis and impaired renal function. In the lungs, it can result in reduced gas exchange efficiency.