What are the histological techniques used to study ESCO2?
Several histological techniques are employed to study the effects of ESCO2 on tissues:
Immunohistochemistry (IHC): This technique uses antibodies to detect ESCO2 protein expression in tissue sections. In Situ Hybridization (ISH): This method allows for the localization of ESCO2 mRNA within tissue samples. Electron Microscopy (EM): EM provides a detailed view of cellular structures, facilitating the observation of chromatid cohesion defects at a microscopic level.