What are the Histological Side Effects of Antiarrhythmic Medications?
While antiarrhythmic medications are beneficial, they may also induce histological changes that could be detrimental:
- Class I: These drugs can cause changes in the morphology of cardiac myocytes, potentially leading to arrhythmogenic effects. - Class II: Prolonged use might result in structural changes in the myocardium, such as fibrosis. - Class III: Drugs like amiodarone can cause cellular toxicity and histological alterations in various organs, including the lungs and liver. - Class IV: These medications may induce changes in the smooth muscle cells of blood vessels, influencing vascular tone.
