What are the Histological Features of Neuropathies?
Neuropathies can manifest through several histological changes. A common feature is the degeneration of axons and myelin sheaths. This may appear as axonal degeneration, where the axons shrink and fragment, or demyelination, where the protective myelin sheath is damaged or lost. Inflammatory cells, such as macrophages, may infiltrate the nerve tissue to clear debris, a process known as Wallerian degeneration.
