What are the Histological Features of Neuronal Damage?
The histological features of neuronal damage can vary depending on the cause and extent of the injury. Common features include:
- Chromatolysis: Dissolution of Nissl bodies and swelling of the neuron. - Pyknosis: Condensation of the nucleus leading to cell death. - Gliosis: Proliferation of glial cells in response to neuronal injury. - Axonal Spheroids: Swollen axons indicating disrupted transport. - Neurofibrillary Tangles: Aggregated proteins often seen in Alzheimer's disease.
