malignant transformation

What are the Histological Features of Malignant Cells?

Under the microscope, malignant cells exhibit distinct histological features:
Nuclear Atypia: Abnormalities in the size, shape, and staining properties of the nucleus.
Increased Nucleus to Cytoplasm Ratio: The nucleus occupies a larger portion of the cell volume compared to normal cells.
Mitoses: Increased number of mitotic figures, often including abnormal mitoses.
Loss of Differentiation: Cells appear less specialized and more primitive in form.
Invasion: Evidence of cells infiltrating surrounding tissues.

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