What Are the Histological Features of Follicular Lymphoma?
Follicular lymphoma typically presents with a nodular or follicular pattern in lymph node biopsies. Histologically, the lymph nodes show an overgrowth of abnormal follicles, which are composed of small cleaved cells and large cells. The presence of the t(14;18) translocation can often be confirmed using immunohistochemical staining for BCL2 protein, which will be positive in these cells.