What Are the Histological Features of Duchenne Muscular Dystrophy?
In Duchenne Muscular Dystrophy, histological examination of muscle tissue typically shows:
- Muscle Fiber Degeneration: Muscle fibers appear necrotic and are replaced by fat and connective tissue. - Inflammatory Infiltrates: Presence of immune cells indicates ongoing muscle damage and repair attempts. - Variation in Fiber Size: Muscle fibers show significant variability in size, reflecting the regenerative attempts of the muscle.