What Are the Histological Changes in the Vaginal Epithelium?
In the vaginal epithelium, estrogen therapy leads to increased epithelial thickness, enhanced glycogen content, and improved vascularization. These changes result in reduced atrophy, increased lubrication, and overall improved vaginal health. Histologically, the epithelium appears more stratified, with a well-defined basal layer and increased superficial cell layers.
