What are the Histological Changes in Acute vs. Chronic Renal Toxicity?
Acute renal toxicity is often marked by tubular necrosis and acute inflammation. In contrast, chronic renal toxicity exhibits more long-term changes such as interstitial fibrosis, chronic inflammation, and glomerulosclerosis. While acute changes are generally reversible if the toxic exposure is halted, chronic changes can lead to permanent renal damage and loss of function.
