What are the Future Directions in Gamma Secretase Research?
Future research on the gamma secretase complex aims to better understand its structure-function relationship and regulatory mechanisms. Advances in cryo-electron microscopy have provided detailed insights into the complex's structure, which could aid in the design of more selective inhibitors or modulators. Moreover, further elucidation of gamma secretase's role in various diseases beyond Alzheimer's, such as cancer, could open new avenues for therapeutic development.
