What are the Future Directions for Bioluminescence Imaging in Histology?
The future of BLI in histology looks promising with ongoing advancements in technology and methodology. Some potential directions include:
Improved luciferase variants: Developing luciferase enzymes with enhanced brightness and stability. Multimodal imaging: Combining BLI with other imaging modalities, such as fluorescence and MRI, to provide complementary information. Deep tissue imaging: Enhancing tissue penetration through the use of red-shifted luciferases or novel imaging techniques. Automated analysis: Utilizing machine learning and artificial intelligence to automate the analysis of BLI data.
