What Techniques are Used to Study Ultrastructures?
The primary techniques used to study ultrastructures are Electron Microscopy (EM) and Cryo-electron Microscopy (Cryo-EM). Electron microscopy involves using a beam of electrons to create highly magnified images of cellular structures. TEM provides detailed images of thin sections of specimens, revealing internal structures, while SEM offers three-dimensional views of surfaces. Cryo-EM, on the other hand, allows for the imaging of specimens in a near-native state without the need for chemical fixation or staining.