What are the Consequences of Incorrect Ionic Strength?
Incorrect ionic strength in histological procedures can lead to several issues:
- Poor tissue preservation: Inadequate fixation due to improper ionic strength can result in tissue degradation and loss of structural integrity. - Suboptimal staining: Incorrect ionic strength can cause uneven staining, high background noise, or weak signal, making it difficult to interpret the histological sections. - Altered enzyme activity: Enzyme-based techniques may yield false-positive or false-negative results if the ionic strength is not optimized for the specific enzyme used.
