The minimal matrix typically includes a few key components:
1. Collagen: The most abundant protein in the ECM, providing tensile strength and structural support. 2. Elastin: Confers elasticity to tissues such as skin, lungs, and blood vessels. 3. Fibronectin: A glycoprotein that helps in cell adhesion and migration. 4. Laminin: Important for basement membrane structure and cell differentiation. 5. Proteoglycans: Provide hydration and compressive resistance to tissues.