Common causes of cell cycle dysregulation include: 1. Genetic Mutations: Mutations in genes encoding for cyclins, CDKs, or tumor suppressors can lead to loss of control over the cell cycle. 2. Epigenetic Changes: Alterations in DNA methylation and histone modification can inactivate tumor suppressor genes or activate oncogenes. 3. Viral Infections: Certain viruses can integrate into the host genome and disrupt regulatory pathways. 4. Environmental Factors: Exposure to radiation, toxins, or carcinogens can induce mutations or alter signaling pathways.
