What are the clinical implications of TP53 mutations?
Mutations in TP53 have significant clinical implications. They are associated with various types of cancer, including breast, lung, colorectal, and ovarian cancers. TP53 status can influence the prognosis of cancer patients and their response to treatment. For instance, cancers with TP53 mutations often have a poorer prognosis and may be more resistant to conventional therapies such as chemotherapy and radiation.
