What are the Clinical Implications of Poikilocytosis?
The presence of poikilocytosis can have several clinical implications. Since poikilocytes are often less efficient at transporting oxygen, patients may experience symptoms such as fatigue, weakness, and shortness of breath. The specific clinical implications depend on the underlying cause:
- Sickle Cell Anemia: Patients may suffer from pain crises, increased risk of infection, and organ damage. - Thalassemia: Chronic anemia, bone deformities, and growth delays are common. - Vitamin Deficiencies: Patients may exhibit symptoms of anemia, such as pallor and lethargy, alongside other signs specific to the deficient vitamin.
